03 / TECHNOLOGY

Technology

OUR APPROACH

From patients to treatment.

From research grounded in human disease to therapies designed to act on underlying causes, we connect distinct technologies in one continuous process.

  1. 01 PATIENT-DERIVED CELLS
    Cell culture work: pipetting culture medium into a multiwell plate

    Patient-derived cells

    Disease information carried by patient cells forms the starting point of our research.

  2. 02 iPS TECHNOLOGY
    Disease research with iPS cells

    Disease research with iPS cells

    We derive disease-relevant cells and observe pathological processes at the cellular level.

  3. 03 DISEASE INSIGHT
    Therapeutic insight

    Therapeutic insight

    We deepen our understanding of disease and search for ways to act on its underlying causes.

  4. 04 THERAPEUTIC MODALITIES
    Translation into therapeutic approaches

    Translation into therapeutic approaches

    We connect scientific insight to gene therapies such as base editing that pursue fundamental treatment.

RESEARCH FOUNDATIONS

From disease insight to therapeutic design

Patient-derived iPS cells provide a platform for disease modeling and candidate evaluation. We connect those findings to therapeutic approaches such as base editing that act on causal DNA variants.

01

iPS TECHNOLOGY

Model disease and evaluate candidates

Patient-derived iPS cells are differentiated into disease-relevant cells to reproduce human pathology and support target discovery, efficacy evaluation, and toxicity assessment.

02

BASE EDITING

Repair a causal DNA variant

Base editing changes a selected nucleotide without making a DNA double-strand break, providing an approach to directly correct a disease-causing variant.

INFORMATION

About our research

Disease-model development and therapeutic candidate evaluation using patient-derived iPS cells are available for discussion as research services. Feasibility is assessed for each objective.

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